{"product_id":"reed-biotech-trap230-polyclonal-antibody-ra35495","title":"TRAP230 Polyclonal Antibody","description":"\u003cp\u003emediator complex subunit 12(MED12) Homo sapiens The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by this gene, mediator complex subunit 12 (MED12), along with MED13, CDK8 kinase, and cyclin C. The CDK8 subcomplex modulates Mediator-polymerase II interactions and thereby regulates transcription initiation and reinitation rates. The MED12 protein is essential for activating CDK8 kinase. Defects in this gene cause X-linked Opitz-Kaveggia syndrome, also known as FG syndrome, and Lujan-Fryns syndrome. [provided by RefSeq, Aug 2009],\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250220933460,"sku":"ABM5039889-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250220966228,"sku":"ABM5039889-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody_1_a488ad62-d2b4-4398-9c27-3d334e77dfd3.webp?v=1790235410","url":"https:\/\/www.abmium.com\/fr\/products\/reed-biotech-trap230-polyclonal-antibody-ra35495","provider":"ABMIUM","version":"1.0","type":"link"}