{"product_id":"reed-biotech-sik2-polyclonal-antibody-ra34861","title":"SIK2 Polyclonal Antibody","description":"\u003cp\u003ecatalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.,similarity:Belongs to the protein kinase superfamily. CAMK Ser\/Thr protein kinase family. AMPK subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 UBA domain.,subunit:Interacts with and phosphorylates TORC2\/CRTC2.,\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250203894100,"sku":"ABM5039255-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250203926868,"sku":"ABM5039255-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody_1_01c35563-865f-413f-a35c-a485786f47d7.webp?v=1790235182","url":"https:\/\/www.abmium.com\/fr\/products\/reed-biotech-sik2-polyclonal-antibody-ra34861","provider":"ABMIUM","version":"1.0","type":"link"}