{"product_id":"reed-biotech-pcsk9-rabbit-polyclonal-antibody-ra28591","title":"PCSK9 Rabbit Polyclonal Antibody","description":"\u003cp\u003ecofactor:Calcium.,disease:Defects in PCSK9 are the cause of familial hypercholesterolemia 3 (FH3) [MIM:603776]. FH3 inheritance is autosomal dominant.,enzyme regulation:Inhibited by EGTA.,function:May be implicated in the differentiation of cortical neurons and may play a role in cholesterol homeostasis.,PTM:The soluble zymogen undergoes autocatalytic intramolecular processing in the endoplasmic reticulum, resulting in the cleavage of its propeptide that remains associated with the secreted enzyme.,similarity:Belongs to the peptidase S8 family.,similarity:Contains 1 peptidase S8 domain.,subunit:The precursor protein but not the mature protein may form multimers.,tissue specificity:Expressed in neuro-epithelioma, colon carcinoma, hepatic and pancreatic cell lines, and in Schwann cells.,\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250078490964,"sku":"ABM5032985-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250078523732,"sku":"ABM5032985-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody_1_8d618cf0-39ab-4481-b323-1ce73490d04c.webp?v=1790234843","url":"https:\/\/www.abmium.com\/fr\/products\/reed-biotech-pcsk9-rabbit-polyclonal-antibody-ra28591","provider":"ABMIUM","version":"1.0","type":"link"}