{"product_id":"reed-biotech-pcbp1-polyclonal-antibody-ra34002","title":"PCBP1 Polyclonal Antibody","description":"\u003cp\u003epoly(rC) binding protein 1(PCBP1) Homo sapiens This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5\u0026amp;apos;-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. Th\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250596028756,"sku":"ABM5038396-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250596061524,"sku":"ABM5038396-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody_1_af8668ec-b769-419b-80ae-93d8c3fbe80d.webp?v=1790234835","url":"https:\/\/www.abmium.com\/fr\/products\/reed-biotech-pcbp1-polyclonal-antibody-ra34002","provider":"ABMIUM","version":"1.0","type":"link"}