{"product_id":"reed-biotech-hdac5-phospho-ser498-polyclonal-antibody-ra25659","title":"HDAC5 (phospho Ser498) Polyclonal Antibody","description":"\u003cp\u003ehistone deacetylase 5(HDAC5) Homo sapiens Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation\/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase\/acuc\/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57249647984980,"sku":"ABM5030053-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57249648017748,"sku":"ABM5030053-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/fr\/products\/reed-biotech-hdac5-phospho-ser498-polyclonal-antibody-ra25659","provider":"ABMIUM","version":"1.0","type":"link"}