{"product_id":"reed-biotech-gbb3-polyclonal-antibody-ra32416","title":"GBB3 Polyclonal Antibody","description":"\u003cp\u003eG protein subunit beta 3(GNB3) Homo sapiens Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit which belongs to the WD repeat G protein beta family. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Alternative splicing results in multiple transcript variants. Additional alternatively spliced tr\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250511552852,"sku":"ABM5036810-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250511585620,"sku":"ABM5036810-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/fr\/products\/reed-biotech-gbb3-polyclonal-antibody-ra32416","provider":"ABMIUM","version":"1.0","type":"link"}