{"product_id":"reed-biotech-col25a1-polyclonal-antibody-ra23637","title":"COL25A1 Polyclonal Antibody","description":"\u003cp\u003ecollagen type XXV alpha 1 chain(COL25A1) Homo sapiens This gene encodes a brain-specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over-expression of this collagen in mice, however, found changes in pathology and behavior suggesting that the encoded protein may promote amyloid plaque formation (PMID: 19548013). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57251091808596,"sku":"ABM5028031-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57251091841364,"sku":"ABM5028031-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/fr\/products\/reed-biotech-col25a1-polyclonal-antibody-ra23637","provider":"ABMIUM","version":"1.0","type":"link"}