{"product_id":"reed-biotech-cleaved-integrin-alpha6-lc-e942-polyclonal-antibody-ra23496","title":"Cleaved-Integrin α6 LC (E942) Polyclonal Antibody","description":"\u003cp\u003eintegrin subunit alpha 6(ITGA6) Homo sapiens The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2\/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250195669332,"sku":"ABM5027890-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250195702100,"sku":"ABM5027890-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/fr\/products\/reed-biotech-cleaved-integrin-alpha6-lc-e942-polyclonal-antibody-ra23496","provider":"ABMIUM","version":"1.0","type":"link"}