{"product_id":"reed-biotech-arrestin-beta-1-phospho-ser412-polyclonal-antibody-ra22093","title":"Arrestin-β-1 (phospho Ser412) Polyclonal Antibody","description":"\u003cp\u003earrestin beta 1(ARRB1) Homo sapiens Members of arrestin\/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK\/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011],\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250409251156,"sku":"ABM5026487-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250409283924,"sku":"ABM5026487-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/fr\/products\/reed-biotech-arrestin-beta-1-phospho-ser412-polyclonal-antibody-ra22093","provider":"ABMIUM","version":"1.0","type":"link"}