{"product_id":"rabbit-polyclonal-antibody-to-uap1-p09295","title":"Anti-UAP1 Rabbit Polyclonal Antibody","description":"\u003cp\u003ecatalyses the last step in biosynthesis of uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) by converting UTP and glucosamine 1-phosphate (GlcNAc-1-P) to the sugar nucleotide. Also converts UTP and galactosamine 1-phosphate (GalNAc-1-P) into uridine diphosphate-N-acetylgalactosamine (UDP-GalNAc). In addition to its role in metabolism, acts as a regulator of innate immunity in response to virus infection by mediating pyrophosphorylation of IRF3: catalyses pyrophosphorylation of IRF3 phosphorylated at 'Ser-386' by TBK1, promoting IRF3 dimerization and activation, leading to type I interferon responses.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58006930817364,"sku":"ABM404677-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58006930850132,"sku":"ABM404677-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58006930882900,"sku":"ABM404677-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/fr\/products\/rabbit-polyclonal-antibody-to-uap1-p09295","provider":"ABMIUM","version":"1.0","type":"link"}