{"product_id":"rabbit-polyclonal-antibody-to-tab2-p33166","title":"Anti-TAB2 Rabbit Polyclonal Antibody","description":"\u003cp\u003eAdapter required to activate the JNK and NF-kappa-B signalling pathways through the specific recognition of 'Lys-63'-linked polyubiquitin chains by its RanBP2-type zinc finger (NZF). TAB2 acts as an adapter linking MAP3K7\/TAK1 and TRAF6 to 'Lys-63'-linked polyubiquitin chains. The RanBP2-type zinc finger (NZF) specifically recognizes 'Lys-63'-linked polyubiquitin chains unanchored or anchored to the substrate proteins such as RIPK1\/RIP1 and RIPK2: this acts as a scaffold to organize a large signalling complex to promote autophosphorylation of MAP3K7\/TAK1, and subsequent activation of I-kappa-B-kinase (IKK) core complex by MAP3K7\/TAK1.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58157046759764,"sku":"ABM416094-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58157046792532,"sku":"ABM416094-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58157046825300,"sku":"ABM416094-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/fr\/products\/rabbit-polyclonal-antibody-to-tab2-p33166","provider":"ABMIUM","version":"1.0","type":"link"}