{"product_id":"rabbit-polyclonal-antibody-to-rnf144a-p52078","title":"Anti-RNF144A Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eRNF144A\u003c\/strong\u003e is an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. RNF144A mediates the ubiquitination and degradation of the DNA damage kinase PRKDC during DNA damage. Positively regulates DNA virus or exogenous cytosolic DNA-triggered innate immune response by mediating STING1 ubiquitination and increasing its 'Lys-6'-linked ubiquitination and translocation from the endoplasmic reticulum to the Golgi leading to downstream signalling pathways.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58168894423380,"sku":"ABM421149-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58168894456148,"sku":"ABM421149-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58168894488916,"sku":"ABM421149-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/fr\/products\/rabbit-polyclonal-antibody-to-rnf144a-p52078","provider":"ABMIUM","version":"1.0","type":"link"}