{"product_id":"rabbit-polyclonal-antibody-to-pum2-n-term-p30314","title":"Anti-PUM2 (N-term) Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003ePUM2\u003c\/strong\u003e is a sequence-specific RNA-binding protein that acts as a post-transcriptional repressor by binding the 3'-UTR of mRNA targets. PUM2 binds to an RNA consensus sequence, the Pumilio Response Element (PRE), 5'-UGUANAUA-3', that is related to the Nanos Response Element (NRE) (, PubMed:21397187). PUM2 mediates post-transcriptional repression of transcripts via different mechanisms: acts via direct recruitment of the CCR4-POP2-NOT deadenylase leading to translational inhibition and mRNA degradation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58031245689172,"sku":"ABM413564-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58031245721940,"sku":"ABM413564-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58031245754708,"sku":"ABM413564-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/enP303142.jpg?v=1793236654","url":"https:\/\/www.abmium.com\/fr\/products\/rabbit-polyclonal-antibody-to-pum2-n-term-p30314","provider":"ABMIUM","version":"1.0","type":"link"}