{"product_id":"rabbit-polyclonal-antibody-to-pras40-phospho-ser183-p44149","title":"Anti-PRAS40 (phospho-Ser183) Rabbit Polyclonal Antibody","description":"\u003cp\u003eNegative regulator of the mechanistic target of rapamycin complex 1 (mTORC1), an evolutionarily conserved central nutrient sensor that stimulates anabolic reactions and macromolecule biosynthesis to promote cellular biomass generation and growth. In absence of insulin and nutrients, AKT1S1 associates with the mTORC1 complex and directly inhibits mTORC1 activity by blocking the MTOR substrate-recruitment site. In response to insulin and nutrients, AKT1S1 dissociates from mTORC1.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58167900766548,"sku":"ABM420797-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58167900799316,"sku":"ABM420797-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58167900832084,"sku":"ABM420797-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/fr\/products\/rabbit-polyclonal-antibody-to-pras40-phospho-ser183-p44149","provider":"ABMIUM","version":"1.0","type":"link"}