{"product_id":"rabbit-polyclonal-antibody-to-nnt1-p23337","title":"Anti-NNT1 Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eCLCF1\u003c\/strong\u003e functions as a cytokine, either alone or by forming a stable complex with soluble CRLF1 or CNTFR. CLCF1 binds to CNTFR complex (CNTFR, IL6ST\/gp130, LIFR) or can signal via trans-signalling using soluble CNTFR subunits. Mechanistically, ligand binding to CNTFR, induces dimerization of the IL6ST\/gp130 and LIFR, which activates JAK tyrosine kinases (JAK1 or JAK2 and to lesser extent TYK2) bound to their intracellular domains.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58031144632660,"sku":"ABM413057-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58031144665428,"sku":"ABM413057-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58031144698196,"sku":"ABM413057-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/fr\/products\/rabbit-polyclonal-antibody-to-nnt1-p23337","provider":"ABMIUM","version":"1.0","type":"link"}