{"product_id":"rabbit-polyclonal-antibody-to-aste1-p10093","title":"Anti-ASTE1 Rabbit Polyclonal Antibody","description":"\u003cp\u003eStructure-specific DNA endonuclease that specifically cleaves single-stranded DNA and 3' overhang DNA. ASTE1 contributes to the control of DNA double-strand break repair choice by antagonizing BRCA1-dependent homologous recombination (HR) and promoting non-homologous end-joining (NHEJ). Recruited to the single-stranded DNA ends by SHLD2 and cleaves the 3' exposed DNA ends, therefore inhibiting DNA end resection (necessary for HR) and promoting DNA end protection (necessary for NHEJ).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58007048356180,"sku":"ABM405330-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58007048388948,"sku":"ABM405330-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58007048421716,"sku":"ABM405330-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/fr\/products\/rabbit-polyclonal-antibody-to-aste1-p10093","provider":"ABMIUM","version":"1.0","type":"link"}