{"product_id":"rabbit-polyclonal-antibody-to-armc5-p30677","title":"Anti-ARMC5 Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eARMC5\u003c\/strong\u003e is a substrate-recognition component of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes. The BCR(ARMC5) complex provides a quality checkpoint during transcription elongation by driving premature transcription termination of transcripts that are unfavorably configured for transcriptional elongation: the BCR(ARMC5) complex acts by mediating ubiquitination of Pol II subunit POLR2A phosphorylated at 'Ser-5' of the C-terminal domain (CTD), leading to POLR2A degradation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58031302345044,"sku":"ABM413903-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58031302377812,"sku":"ABM413903-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58031302410580,"sku":"ABM413903-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/fr\/products\/rabbit-polyclonal-antibody-to-armc5-p30677","provider":"ABMIUM","version":"1.0","type":"link"}