{"product_id":"rabbit-polyclonal-antibody-to-aim2-p42163","title":"Anti-AIM2 Rabbit Polyclonal Antibody","description":"\u003cp\u003eSensor component of the AIM2 inflammasome, which mediates inflammasome activation in response to the presence of double-stranded DNA (dsDNA) in the cytosol, leading to subsequent pyroptosis. Inflammasomes are supramolecular complexes that assemble in the cytosol in response to pathogens and other damage-associated signals and play critical roles in innate immunity and inflammation. AIM2 acts as a recognition receptor (PRR): specifically recognizes and binds dsDNA in the cytosol, and mediates the formation of the inflammasome polymeric complex composed of AIM2, CASP1 and PYCARD\/ASC.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58163244106068,"sku":"ABM419237-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58163244138836,"sku":"ABM419237-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58163244171604,"sku":"ABM419237-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/fr\/products\/rabbit-polyclonal-antibody-to-aim2-p42163","provider":"ABMIUM","version":"1.0","type":"link"}