{"product_id":"proteogenix-cd132-recombinant-protein","title":"CD132 Recombinant Protein","description":"\u003ch2\u003eGeneral information on CD132 Recombinant Protein:\u003c\/h2\u003e \u003cp\u003e The common gamma chain (γc) (or CD132), also known as the interleukin 2 receptor γ or IL2RG subunit, is a member of the type I cytokine family and is expressed in most lymphocytes (leukocytes) and its cells in mammals. A gene was found on its X chromosome. The common γ (γc) chain (or IL2RG) is the cytokine receptor subunit, which is the cytokine receptor subunit shared by the receptor complexes of at least six different interleukin receptors. IL-2, IL-4, IL-7, IL-9, IL-15 and interleukin 21 receptors. It is a component of many cytokine receptors, which are essential for the development and function of lymphocytes. Severe X-linked combined immunodeficiency (XSCID) is a rare and life-threatening disease caused by mutations in IL2RG (the gene that encodes IL2RG). Based on chemical binding data, IL2RG has been shown to be a component of the IL-4 receptor, that is, the ability of IL2RG to increase IL-4 binding affinity. The observation that the IL-2R range is a functional part of the IL-4 receptor, and the discovery that IL-2Rγ is related to the IL-7 receptor, began to explain why the lack of this γ chain common (γc) has an impact on lymphatic development and function. It has a profound impact, as seen in X-linked severe combined immunodeficiency.\u003c\/p\u003e\u003cp\u003eProteoGenix catalogue number PX-P4105. For research use only.\u003c\/p\u003e\u003cp\u003eHost: Mammalian cells; Expression system: Eukaryotic expression; Purity: \u0026gt;90% by SDS-PAGE; Molecular weight: 30.70kDa; Tag: C-terminal His Tag; Fragment: Met1-Asn254; Buffer: PBS pH7.5; Applications: ELISA, WB.\u003c\/p\u003e\u003cp\u003eAvailable configurations: 50ug, 100ug, 1mg.\u003c\/p\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.proteogenix.science\/wp-content\/uploads\/documents\/Datasheets\/PX-P4105.pdf\"\u003eDownload the manufacturer datasheet\u003c\/a\u003e\u003c\/p\u003e","brand":"ProteoGenix","offers":[{"title":"50ug","offer_id":57376231817556,"sku":"ABM146408-1","price":172.0,"currency_code":"GBP","in_stock":true},{"title":"100ug","offer_id":57376231850324,"sku":"ABM146408-2","price":231.2,"currency_code":"GBP","in_stock":true},{"title":"1mg","offer_id":57376231883092,"sku":"ABM146408-3","price":759.2,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/3d-representation-image-cd132-recombinant-protein.webp?v=1790896790","url":"https:\/\/www.abmium.com\/fr\/products\/proteogenix-cd132-recombinant-protein","provider":"ABMIUM","version":"1.0","type":"link"}