{"product_id":"abm218720","title":"Human Nicastrin, NCSTN ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eEssential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed: 10993067, PubMed: 12679784, PubMed: 25043039, PubMed: 26280335, PubMed: 30598546, PubMed: 30630874). The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661987455316,"sku":"ABM218720","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661987488084,"sku":"ABM218721","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-cd4195a4b29c5d356bd89bce5b89a537d3ff55c62693d63760acb717016024ac.jpg?v=1792159230","url":"https:\/\/www.abmium.com\/fr\/products\/abm218720","provider":"ABMIUM","version":"1.0","type":"link"}