{"product_id":"abm216680","title":"Human Immediate Early Response Gene 5 Protein, IER5 ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003ePlays a role as a transcription factor (PubMed: 22132193, PubMed: 25355627). Mediates positive transcriptional regulation of several chaperone genes during the heat shock response in a HSF1-dependent manner (PubMed: 25355627, PubMed: 25816751). Mediates negative transcriptional regulation of CDC25B expression (PubMed: 22132193). Plays a role in the dephosphorylation of the heat shock factor HSF1 and ribosomal protein S6 kinase (S6K) by the protein phosphatase PP2A (PubMed: 25816751, PubMed: 26496226). Involved in the regulation of cell proliferation and resistance to thermal stress (PubMed: 22132193, PubMed: 25355627, PubMed: 26496226). Involved in the cell cycle checkpoint and survival in response to ionizing radiation (PubMed: 19238419, PubMed: 22132193). Associates with chromatin to the CDC25B promoter (PubMed: 22132193).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661945872724,"sku":"ABM216680","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661945905492,"sku":"ABM216681","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-7acede5a058eb166d84264a2fed9a637018aa06f7c0209057abf7e0051b5eded.jpg?v=1792159235","url":"https:\/\/www.abmium.com\/fr\/products\/abm216680","provider":"ABMIUM","version":"1.0","type":"link"}