{"product_id":"abm216098","title":"Human Coiled-Coil Domain-containing Protein 134, CCDC134 ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eIn extracellular secreted form, promotes proliferation and activation of CD8(+) T cells, suggesting a cytokine-like function (PubMed: 25125657). Enhances cytotoxic anti-tumor activity of CD8(+) T cells (PubMed: 25125657). May inhibit ERK and JNK signaling activity (PubMed: 18087676, PubMed: 23070808). May suppress cell migration and invasion activity, via its effects on ERK and JNK signaling (PubMed: 23070808). In the nucleus, enhances stability of the PCAF histone acetyltransferase (HAT) complex member TADA2A and thus promotes PCAF-mediated H3K14 and H4K8 HAT activity. May inhibit TADA2A-mediated TP53\/p53 'Lys-321' acetylation, leading to reduced TP53 stability and transcriptional activity. May also promote TADA2A-mediated XRCC6 acetylation thus facilitating cell apoptosis in response to DNA damage.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661989388628,"sku":"ABM216098","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661989421396,"sku":"ABM216099","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-b75107d40822c5e2882856fc8f79898e72e2246654c43d6125816c25dd682f82.jpg?v=1792159241","url":"https:\/\/www.abmium.com\/fr\/products\/abm216098","provider":"ABMIUM","version":"1.0","type":"link"}