{"product_id":"abm213692","title":"Rat Eukaryotic Translation Initiation Factor 4E, EIF4E ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eRecognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures (PubMed:7939721). In addition to its role in translation initiation, also acts as a regulator of translation and stability in the cytoplasm (PubMed:8558852). Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression: in the complex, EIF4E mediates the binding to the mRNA cap. Component of a multiprotein complex that sequesters and represses translation of proneurogenic factors during neurogenesis (By similarity). In P-bodies, component of a complex that mediates the storage of translationally inactive mRNAs in the cytoplasm and prevents their degradation (By similarity). May play an important role in spermatogenesis through translational regulation of stage-specific mRNAs during germ cell development (PubMed:8558852).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661605478740,"sku":"ABM213692","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661605511508,"sku":"ABM213693","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-b38984aee1adcaa78bf5b97e3b4d06eb0899b4f2cbae522d7ab12a709cbd575e.jpg?v=1792159221","url":"https:\/\/www.abmium.com\/fr\/products\/abm213692","provider":"ABMIUM","version":"1.0","type":"link"}