{"product_id":"abm213042","title":"Human Anthrax Toxin Receptor 2, ANTXR2 ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eNecessary for cellular interactions with laminin and the extracellular matrix. (Microbial infection) Receptor for the protective antigen (PA) of B.anthracis (PubMed:12700348, PubMed:15243628, PubMed:15326297). Binding of PA leads to heptamerization of the receptor-PA complex (PubMed:12700348, PubMed:15243628, PubMed:15326297). Upon binding of the PA of B.anthracis, the complex moves to glycosphingolipid-rich lipid rafts, where it is internalized via a clathrin-dependent pathway (PubMed:12551953, PubMed:15337774). In the endosomal membrane, at pH under 7, the complex then rearranges and forms a pore allowing the other components of anthrax toxin to escape to the cytoplasm (PubMed:12551953, PubMed:15337774).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661609345364,"sku":"ABM213042","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661609378132,"sku":"ABM213043","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-bba03f55d54ef4c4ed061f7e6fc1ca86e44a61a207e8383cb106f07bce047567.jpg?v=1792159223","url":"https:\/\/www.abmium.com\/fr\/products\/abm213042","provider":"ABMIUM","version":"1.0","type":"link"}