{"product_id":"abm211478","title":"Human Ryanodine Receptor 1, RYR1 ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eCalcium Channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules (PubMed: 11741831, PubMed: 16163667). Repeated very high-level exercise increases the open probability of the Channel and leads to Ca(2+) leaking into the cytoplasm (PubMed: 18268335). Can also mediate the release of Ca(2+) from intracellular stores in neurons, and may thereby promote prolonged Ca(2+) signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. Required for normal heart morphogenesis, skin development and ossification during embryogenesis (By similarity).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661977690452,"sku":"ABM211478","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661977723220,"sku":"ABM211479","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-c727a97a346a520f95c522e0e6f1013e2effe5ef47a24598355ca39d1042159d.jpg?v=1792159211","url":"https:\/\/www.abmium.com\/fr\/products\/abm211478","provider":"ABMIUM","version":"1.0","type":"link"}