{"product_id":"abm209164","title":"Mouse Protein O-Glucosyltransferase 1, POGLUT1 ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eDual specificity glycosyltransferase that catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose, respectively, to a serine residue found in the consensus sequence of C-X-S-X-P-C (PubMed: 21949356, PubMed: 26496195). Specifically targets extracellular EGF repeats of protein such as CRB2, F7, F9 and NOTCH2 (PubMed: 21949356, PubMed: 26496195). Acts as a positive regulator of Notch signaling by mediating O-glucosylation of Notch, leading to regulate muscle development (By similarity). Notch glucosylation does not affect Notch ligand binding (By similarity). Required during early development to promote gastrulation: acts by mediating O-glucosylation of CRB2, which is required for CRB2 localization to the cell membrane (PubMed: 26496195).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661591290196,"sku":"ABM209164","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661591322964,"sku":"ABM209165","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-f25dfa1b8b23c52e47d40646a1c982db49d66e24818dd32135c472d01bc92a91.jpg?v=1792159235","url":"https:\/\/www.abmium.com\/fr\/products\/abm209164","provider":"ABMIUM","version":"1.0","type":"link"}