{"product_id":"abm208862","title":"Rat Chromogranin-A, CGA ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eStrongly inhibits glucose induced insulin release from the pancreas. Catestatin inhibits catecholamine release from chromaffin cells and noradrenergic neurons by acting as a non-competitive nicotinic cholinergic antagonist. Can induce mast cell migration, degranulation and production of cytokines and chemokines. Serpinin regulates granule biogenesis in endocrine cells by up-regulating the transcription of protease nexin 1 (SERPINE2) via a cAMP-PKA-SP1 pathway. This leads to inhibition of granule protein degradation in the Golgi complex which in turn promotes granule formation (By similarity). Serpinin and pGlu-serpinin can enhance both myocardial contractility (inotropy) and relaxation (lusitropy) and this cardio-stimulation requires a beta 1-adrenergic receptor\/adenylate cyclase\/cAMP\/PKA pathway (PubMed:22459152).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661845635412,"sku":"ABM208862","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661845668180,"sku":"ABM208863","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-a837e8f020bd92a05798ce84161b833ae2409b3b57e4867d192bd75e3144dd6a.jpg?v=1792159215","url":"https:\/\/www.abmium.com\/fr\/products\/abm208862","provider":"ABMIUM","version":"1.0","type":"link"}