{"product_id":"abm208540","title":"Human Toll-like Receptor 1, TLR1 ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eParticipates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides (PubMed: 21078852). Forms the activation cluster TLR2:TLR1:CD14 in response to triacylated lipopeptides, this cluster triggers signaling from the cell surface and subsequently is targeted to the Golgi in a lipid-raft dependent pathway (PubMed: 16880211). Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"96T","offer_id":57661604430164,"sku":"ABM208540","price":293.0,"currency_code":"GBP","in_stock":true},{"title":"48T","offer_id":57661604462932,"sku":"ABM208541","price":205.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-9ccd7972e4b265ba594369093f22bfa201c1d03dc9d0565a1c60025d10713cae.jpg?v=1792159162","url":"https:\/\/www.abmium.com\/fr\/products\/abm208540","provider":"ABMIUM","version":"1.0","type":"link"}