{"product_id":"abm206711","title":"Phospho-Caveolin-1 (Y14) Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe scaffolding protein (caveolin 1) encoded by CAV1 is the main component of the caveolae plasma membranes found in most cell types. Caveolin 1 links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. CAV1 is a tumor suppressor gene candidate and a negative regulator of the Ras-p42\/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in CAV1 have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.\u003c\/p\u003e\u003cp\u003e\u003cem\u003ePackaging image shown for reference. Select a size from the available options.\u003c\/em\u003e\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57661432398164,"sku":"ABM206711","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57661432430932,"sku":"ABM206712","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57661432463700,"sku":"ABM206713","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-f324e8429e766fa1531f7fd366db4d43d637484a38050b0923e08284f225198b.jpg?v=1792157294","url":"https:\/\/www.abmium.com\/fr\/products\/abm206711","provider":"ABMIUM","version":"1.0","type":"link"}