{"product_id":"abm203179","title":"HDAC3 Monoclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eHDAC3: histone deacetylase 3, also known as HD3, RPD3, RPD3-2. Entrez Protein NC_000005. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation\/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase\/acuc\/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100μL","offer_id":57661180019028,"sku":"ABM203179","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"50μL","offer_id":57661180051796,"sku":"ABM203180","price":141.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-7e3257cd29abe06c58978691cea9ff0bc3553e5c103ba49a15fd9f7d078ec6a4.jpg?v=1792159129","url":"https:\/\/www.abmium.com\/fr\/products\/abm203179","provider":"ABMIUM","version":"1.0","type":"link"}