{"product_id":"abm202905","title":"TRIB2 Monoclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C\/EBPalpha (CCAAT\/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100μL","offer_id":57660782936404,"sku":"ABM202905","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"50μL","offer_id":57660782969172,"sku":"ABM202906","price":141.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-03372f81a02a55dd05ab5e11d7676600ff3a45a2c71dad9ace0dde73a9855084.jpg?v=1792159152","url":"https:\/\/www.abmium.com\/fr\/products\/abm202905","provider":"ABMIUM","version":"1.0","type":"link"}