{"product_id":"abm202777","title":"PTPN11 Monoclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100μL","offer_id":57661477749076,"sku":"ABM202777","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"50μL","offer_id":57661477781844,"sku":"ABM202778","price":141.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-c0179d40a2e08b1d825733f2cea6413e985be9df0fef326542f664c89dd2ed92.jpg?v=1792159115","url":"https:\/\/www.abmium.com\/fr\/products\/abm202777","provider":"ABMIUM","version":"1.0","type":"link"}