{"product_id":"abm199714","title":"HDAC3 Monoclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation\/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase\/acuc\/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"50ul","offer_id":57660933865812,"sku":"ABM199714","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660933898580,"sku":"ABM199715","price":192.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-96b08e882aa8d18d16cf810bb4ef1bc46acaf994d23e32e3db4a89aa87aa51c7.jpg?v=1792159028","url":"https:\/\/www.abmium.com\/fr\/products\/abm199714","provider":"ABMIUM","version":"1.0","type":"link"}