{"product_id":"abm198251","title":"Girdin(Phospho Ser1417) Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine\/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57661307846996,"sku":"ABM198251","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57661307879764,"sku":"ABM198252","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57661307912532,"sku":"ABM198253","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-ab9214c9c34e66226647a5302d3e17849e4fa598ffd84457726a6b0c9d619914.jpg?v=1792159017","url":"https:\/\/www.abmium.com\/fr\/products\/abm198251","provider":"ABMIUM","version":"1.0","type":"link"}