{"product_id":"abm195806","title":"CENPS Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF(II)31, which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumors, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway. The protein is a component of multiple complexes, including the Fanconi anemia (FA) core complex, the APITD1\/CENPS complex, and the CENPA-CAD (nucleosome distal) complex. Known functions include an involvement with chromatin associations of the FA core complex, and a role in the stable assembly of the outer kinetochore. Alternative splicing of this gene results in multiple transcript variants. Naturally occurring read-through transcripts also exist\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57661302374740,"sku":"ABM195806","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57661302407508,"sku":"ABM195807","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57661302440276,"sku":"ABM195808","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-827f83a2524a0946b0af198bdd396a2f8581a583d2f37f35b87e5783f6efa420.jpg?v=1792158983","url":"https:\/\/www.abmium.com\/fr\/products\/abm195806","provider":"ABMIUM","version":"1.0","type":"link"}