{"product_id":"abm195599","title":"CDA7L Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003ePlays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3\/caspase-3 as well as CCND1\/cyclin D1 and E2F1.,induction:By MYC overexpression in a concentration dependent manner in neuroblastoma cell line.,miscellaneous:Cells lacking CDCA7L display a reduction of 25-30% of colony formation in medulloblastoma cell lines. CDCA7L overexpression induces colony formation.,subcellular location:Associates with chromatin. Translocates from cytoplasm to nucleus under dexamethasone induction.,subunit:Interacts with MYC and PSIP1.,tissue specificity:Ubiquitous. Overexpressed in medulloblastoma.,\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57661154787668,"sku":"ABM195599","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57661154820436,"sku":"ABM195600","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57661154853204,"sku":"ABM195601","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-1ea4c7287cbfdf5088445786c5a5187a69f59f2a2d1db38ede993084a9fd9773.jpg?v=1792241051","url":"https:\/\/www.abmium.com\/fr\/products\/abm195599","provider":"ABMIUM","version":"1.0","type":"link"}