{"product_id":"abm193895","title":"AMPK beta 2 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660789424468,"sku":"ABM193895","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660789457236,"sku":"ABM193896","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660789490004,"sku":"ABM193897","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-ed76c476a907a6d90ea0ee0d240d27387c0a81e8997d972cf69f69e3ba6bf5fe.jpg?v=1792158971","url":"https:\/\/www.abmium.com\/fr\/products\/abm193895","provider":"ABMIUM","version":"1.0","type":"link"}