{"product_id":"abm193892","title":"AMPK alpha2 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660787229012,"sku":"ABM193892","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660787261780,"sku":"ABM193893","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660787294548,"sku":"ABM193894","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-f8dae5c14c197f9e084a5e9a886cfe8d993bfa4a59430e6dd75ef68e9f4842f8.jpg?v=1792158971","url":"https:\/\/www.abmium.com\/fr\/products\/abm193892","provider":"ABMIUM","version":"1.0","type":"link"}