{"product_id":"abm185896","title":"NEDD4L Rabbit Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates| thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel| ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57661105373524,"sku":"ABM185896","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57661105406292,"sku":"ABM185897","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57661105439060,"sku":"ABM185898","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-8315b9f899941e516f9a803baaab519dfd96c570223c2365da69c53083bb8812.jpg?v=1792159044","url":"https:\/\/www.abmium.com\/fr\/products\/abm185896","provider":"ABMIUM","version":"1.0","type":"link"}