{"product_id":"abm180954","title":"F111A Rabbit Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe protein encoded by this gene is cell-cycle regulated| and has nuclear localization. The C-terminal half of the protein shares homology with trypsin-like peptidases and it contains a PCNA-interacting peptide (PIP) box| that is necessary for its co-localization with proliferating cell nuclear antigen (PCNA). Reduced expression of this gene resulted in DNA replication defects| consistent with the demonstrated role for this gene in Simian Virus 40 (SV40) viral replication. Mutations in this gene have been associated with Kenny-Caffey syndrome (KCS) type 2 and the more severe osteocraniostenosis (OCS| also known as Gracile Bone Dysplasia)| both characterized by short stature| hypoparathyroidism| bone development abnormalities| and hypocalcemia. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660008268116,"sku":"ABM180954","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660008300884,"sku":"ABM180955","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660008333652,"sku":"ABM180956","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-aa9f5545340ff6c274e1eeeb80e9d1d0bd09fb9aa70d5879408d04ab4fd25a33.jpg?v=1792159010","url":"https:\/\/www.abmium.com\/fr\/products\/abm180954","provider":"ABMIUM","version":"1.0","type":"link"}