{"product_id":"abm179446","title":"UBE1L Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)\/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57659752841556,"sku":"ABM179446","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57659752874324,"sku":"ABM179447","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57659752907092,"sku":"ABM179448","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-accd0d93ca955b28de7c9de0d47a19dbc0209da185e05070578edd87bc07983c.jpg?v=1792158870","url":"https:\/\/www.abmium.com\/fr\/products\/abm179446","provider":"ABMIUM","version":"1.0","type":"link"}