{"product_id":"abm177856","title":"Tak1 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eMitogen-activated protein kinase kinase kinase 7 encoded by MAP3K7 is a member of the serine\/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1\/TAB1 and MAP3K7P2\/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8\/JNK, MAP2K4\/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660519711060,"sku":"ABM177856","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660519743828,"sku":"ABM177857","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660519776596,"sku":"ABM177858","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-69233d9e123b9928cc6c19607ce3380c6d279b800c9b6d7068db3091921227e3.jpg?v=1792158818","url":"https:\/\/www.abmium.com\/fr\/products\/abm177856","provider":"ABMIUM","version":"1.0","type":"link"}