{"product_id":"abm177370","title":"Stat6 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eSignal transducer and activator of transcription 6 encoded by STAT6 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1\/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660058042708,"sku":"ABM177370","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660058075476,"sku":"ABM177371","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660058108244,"sku":"ABM177372","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-9c8728391c127d143a2b105ec0ea05e51edb8ed376e39f2d89d1959c5b13e106.jpg?v=1792158881","url":"https:\/\/www.abmium.com\/fr\/products\/abm177370","provider":"ABMIUM","version":"1.0","type":"link"}