{"product_id":"abm173839","title":"PSMC6 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP\/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMC6 encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660059713876,"sku":"ABM173839","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660059746644,"sku":"ABM173840","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660059779412,"sku":"ABM173841","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-66ca8860310163d2ecd7a6d5c4719992f11590edfbc6f04cee3b81508b45917e.jpg?v=1792158836","url":"https:\/\/www.abmium.com\/fr\/products\/abm173839","provider":"ABMIUM","version":"1.0","type":"link"}