{"product_id":"abm173266","title":"PLC Gamma1 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003ePhospholipase C gamma 1 encoded by PLCG1 catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, phospholipase C gamma 1 causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, phospholipase C gamma 1 has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for PLCG1.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660634464596,"sku":"ABM173266","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660634497364,"sku":"ABM173267","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660634530132,"sku":"ABM173268","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-4071cabf3339de3bd03b56db2cb1be21ed41e8d74fa7d13539eaa9647d3ff639.jpg?v=1792158878","url":"https:\/\/www.abmium.com\/fr\/products\/abm173266","provider":"ABMIUM","version":"1.0","type":"link"}