{"product_id":"abm172255","title":"c-Myc(Phospho Ser373) Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57659763261780,"sku":"ABM172255","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57659763294548,"sku":"ABM172256","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57659763327316,"sku":"ABM172257","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-96ded4057e1210af97406ace96cbf9051182fe48f04f6390008ea41ea1dbc200.jpg?v=1792158839","url":"https:\/\/www.abmium.com\/fr\/products\/abm172255","provider":"ABMIUM","version":"1.0","type":"link"}