{"product_id":"abm171988","title":"CaMKK2(Phospho-Ser511) Rabbit Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe product of this gene belongs to the Serine\/Threonine protein kinase family| and to the Ca(2+)\/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium\/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory| neuronal differentiation and migration| neurite outgrowth| and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57660600222036,"sku":"ABM171988","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660600254804,"sku":"ABM171989","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57660600287572,"sku":"ABM171990","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-1ea4c7287cbfdf5088445786c5a5187a69f59f2a2d1db38ede993084a9fd9773.jpg?v=1792241051","url":"https:\/\/www.abmium.com\/fr\/products\/abm171988","provider":"ABMIUM","version":"1.0","type":"link"}