{"product_id":"abm170443","title":"BAP1(Phospho-Ser592) Rabbit Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition| the enzyme may be involved in regulation of transcription| regulation of cell cycle and growth| response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS)| which involves increased risk of cancers including malignant mesothelioma| uveal melanoma and cutaneous melanoma.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57660144320852,"sku":"ABM170443","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660144353620,"sku":"ABM170444","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57660144386388,"sku":"ABM170445","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-1ea4c7287cbfdf5088445786c5a5187a69f59f2a2d1db38ede993084a9fd9773.jpg?v=1792241051","url":"https:\/\/www.abmium.com\/fr\/products\/abm170443","provider":"ABMIUM","version":"1.0","type":"link"}