{"product_id":"abm166375","title":"Ku-80 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe protein encoded by XRCC5 (X-ray repair cross complementing 5) is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. XRCC5 functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in XRCC5 is associated with cancer in patients of varying radiosensitivity.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57659873198420,"sku":"ABM166375","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57659873231188,"sku":"ABM166376","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57659873263956,"sku":"ABM166377","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-b0401076757f05553c1cf2a7c7aa0f09da61868da026731b3bdce3c338e5094c.jpg?v=1792158845","url":"https:\/\/www.abmium.com\/fr\/products\/abm166375","provider":"ABMIUM","version":"1.0","type":"link"}