{"product_id":"abm164062","title":"HLA-DOBeta Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eHLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57659887124820,"sku":"ABM164062","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57659887157588,"sku":"ABM164063","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57659887190356,"sku":"ABM164064","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-d8205027f495d35e2ae2551c8ba41a27a02935e1c412a78c9116d8dcd23db034.jpg?v=1792157384","url":"https:\/\/www.abmium.com\/fr\/products\/abm164062","provider":"ABMIUM","version":"1.0","type":"link"}